A continuous glucose monitor is a device used for monitoring blood glucose on a continual basis by people with type I diabetes. A continuous glucose monitor (CGM) takes a reading on set intervals with a small electrode placed under the skin and held in place by an adhesive. A transmitter attached to the electrode sends data to a separate receiver.
Traditional fingerprick testing of blood glucose levels measures the level at a single point in time. CGM use allows trends in blood glucose to be displayed over time. Users must calibrate CGM devices with traditional blood glucose measurements.
A limitation of the CGM system is that glucose levels are taken from the interstitial fluid rather than the blood. As is takes time for glucose to travel from the bloodstream into the interstitial fluid, there is an inherent lag behind the current blood glucose level and the level measured by the CGM. This lag time varies based on the person and the device, and is generally 5-20 minutes.
Video Continuous glucose monitor
History
The first CGM system was approved by the FDA in 1999. Continued development has extended the length of time sensors can be worn, options for receiving and reading data, and settings for alerting users of high and low glucose levels.
The first iteration of the Medtronic MiniMed took glucose readings every ten seconds with average readings reported every five minutes. Sensors could be worn for up to 72 hours.
A second system, developed by Dexcom, was approved in 2006. The sensor was approved for use for up to 72 hours, and the receiver needed to be within five feet for transmission of data. Dexcom released a new device in 2012 that allowed for sensors to be worn for seven days and had a transmission distance of 20 feet. Dexcom later introduced an app allowing data from the sensor to be transmitted to an iPhone. This system was approved for pediatric use in 2015.
In 2008, the third model was approved, Abbott Laboratories' Freestyle Navigator. Sensors could be worn for up to five days.
In September 2017, the FDA approved the first CGM that does not require calibration with fingerstick measurement, the FreeStyle Libre Flash. This device can be worn for up to ten days.
Maps Continuous glucose monitor
Closed loop system
The CGM is a key element in the development of a "closed-loop" system for the treatment of type I diabetes. A closed-loop system involves blood glucose monitored by CGM and the data sent to an insulin pump for calculated delivery of insulin without user intervention.
See also
- Artificial pancreas
References
Source of article : Wikipedia
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